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專題演講：王慧迪 副教授 |
主持人：關超然 教授兼主任 |
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專題演講：王慧迪 副教授 |
專題演講 |
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【教師培育暨發展中心/黃坤堆訊】本校基礎醫學研究所與教師培育暨發展中心、學術交流中心於8月16日（星期四）特別邀請來自加拿大Brock University的王慧迪副教授針對基礎醫學研究所師生進行專題演講，主題為「The role of NADPH oxidase in the release of ET-1 from vascular adventitial fibroblast cell.」，當天師生參與踴躍，會中與王副教授在學術專題上亦互動熱絡，不僅讓教師們可互相分享學術研究成果，亦可提升與增進學生們英文聽寫能力與研究參考。王慧迪副教授簡介資料如下：
CURRICULUM VITAE
HUI-DI WANG, Associate Professor,
Department of Community Health Sciences
Faculty of Applied Health Sciences, Brock University
St. Catharines, ON, Canada, L2S 3A1
Tel: (905) 688-5550 ext 4819
e-mail: huidi.wang@brocku.ca
A. Postdoctoral Experience and Formal Education
Postdoctoral Fellow Boston University Medical Center 1996-2000
Ph.D. University of Saskatchewan, Pharmacology 1990-1995
B.A. Shanghai Medical University 1980-1985
B. Academic Distinctions and Awards
2002-2007: New Investigator Award from Heart and Stroke Foundation of Canada
1998-2000: Cardiovascular Institute Post-Doctoral Fellowship sponsored by National Institute of Health, USA
1991-1994: Training Scholarship from Heart and Stroke Foundation of Canada.
C. Academic Positions
2002-Present Associate Professor, Department of Community Health Sciences, Faculty of Applied Health Sciences, Brock University, St. Catharines, ON, CANADA
2000-2002 Assistant Professor, Department of Pharmacology, College of Medicine, University of Saskatchewan, Saskatoon, SK, CANADA
D. Research Grants:
a. Internal grants
2005-2006 Sole principal investigator (PI), Brock University. (Sum: $35,000)
b. Refereed external grants
2003-2005: Sole PI, operating grant from Canadian Institute of Health Research (Sum: $250,608).
2002-2007: New Investigator Award from Heart and Stroke Foundation of Canada (Sum: $250,000).
2002-2004: Sole PI, operating grant from Canadian Institute of Health Research Regional Partnership Program (CIHR-RPP,. Sum:$236,966, declined: not transferable to Ontario declined).
2001-2003: Sole PI, operating grant from Heart and Stroke Foundation of Canada (Sum: $95,000).
2000-2002 SolePI, establishment grant from Saskatchewan Health Services Utilization and Research Commission (HSURC, Sum :$69,206).
2000: Sole PI, equipment grant, HSURC ($9,573).
E. Selected Peer-Reviewed Publications:
1. Li Li Ding, Alexander Chapman, and Hui Di Wang (2006). ERK Activation Contributes to Regulation of Spontaneous Contractile Tone via Oxidative Stress in Isolated Rat Aorta of Angiotensin II-Induced Hypertension. Am J Physiol Heart Circ Physiol, (revision)
2. Sheng Jun An, Ryan Boyd, Ying Wang, Xiaofan Qiu, and Hui Di Wang (2006) Endothelin-1 Expression in Vascular Adventitial Fibroblasts. Am J Physiol Heart Circ Physiol. Feb;290(2):H700-8.
3. C.Y. Kwan and Hui Di Wang (2006) A look at traditional Chinese Medicine in the modern word. Parkhurst Exchange, Clinical Questions practical answers, Jan, Vol 14 (1), p20-21.
4. Mahua Ghosh, Hui Di Wang, J. Robert McNeill (2004) Role of oxidative stress and nitric oxide in regulation of spontaneous tone in aorta of DOCA-salt hypertensive rats. Br J Pharmacol. Feb;141(4):562-73.
5. Hui Di Wang, D Johns, S Xu, K Maitland and R.A. Cohen, (2002) Role of superoxide anion in regulating pressor and vascular hypertrophic response to angiotensin II. American Journal of Physiology, 282: H1697-H1702.
6. Mahua Ghosh, Hui Di Wang and J. Robert McNeill. (2002). Tiron exerts effects unrelated to its role as a scavenger of superoxide anion: effects on calcium binding and vascular responses. Canadian Journal of Physiology and Pharmacology. 80:755-760, RAPID COMMUNICATION.
7. Shailesh Shastri, Venkat Gopalakrishnan, Ramarao Poduri and Huidi Wang (2002). Tempol selectively attenuates angiotensin II evoked vasoconstrictor responses in spontaneously hypertensive rat. Journal of Hypertension, 20(7): 1381-1391.
8. Huidi Wang, S. Xu, D.G. Johns, Y. Du, M.T. Quinn, A.J. Cayatte and R.A. Cohen, (2001). Role of NADPH oxidase in the vascular hypertrophic and oxidative stress response to angiotensin II in mice. Circ. Res. 88: 947-953.
9. Huidi Wang, S. Hope, Y Du, M.T. Quinn, A.J. Cayatte, P.J. Pagano and R.A. Cohen, (1999). Paracrine role of adventitial superoxide anion in mediating myogenic tone in angiotensin II-induced hypertension. Hypertension 33: 1225-1232.
10. Huidi Wang, P. Pagano, Y.Du, A.J. Cayatte, P. Bretcher and R.A. Cohen, (1998). Superoxide anion from the adventitia of the rat thoracic aorta inactivates nitric oxide. Circ. Res. 82: 810-818.
11. S.M. Balakrishnan, Huidi Wang, V. Gopalakrishnan, T.W. Wilson and J.R. McNeill, (1996). Effect of an Endothelin Antagonist on homodynamic responses to angiotensin II. Hypertension, 28: 806-809.
12. Huidi Wang and J. R. McNeill, (1994). Renal function contributions to the antihypertensive effect of vasopressin in Doca-salt but not spontaneously hypertension. American Journal of Physiology, 267 (36), H1842-H1850.
13. Huidi Wang, N. Wilson, and J.R. McNeill, (1993). Relationship of the antihypertensive effect of vasopressin withdrawal to sodium excretion in the Doca-salt hypertensive rat. Clin. Invest. Med. 16:5 348-357.
14. E.K.Y. Chiu, Huidi Wang, and J.R. McNeill, (1992). Role of sodium and water excretion in the antihyper-tensive effect of vasopressin in the spontaneously hypertensive rat. Can. J. Physiol. Pharmacol. 70, 1309-1334.
F. Invited Presentations (National & International):
1. June, 2006. Role of adventitia in vascular oxidative stress. 11th International Vascular Neuroeffector Mechanisms and Cardiovascular Pharmacology and Medicine Symposia, Shanghai-Suzhou, China
2. June, 2006. NADPH oxidase-derived superoxide anion mediates Angiotension II induced endothelin-1 release from adventitial fibroblasts. Dept. Anesthesia, Fac. Health Sci., McMaster Univ., Canada.
3. October, 2005. ET-1 expression in vascular fibroblast. Invited speaker, 1st International Cardiovascular Research Conference, Shanghai, China.
4. October, 2005. Adventitial fibroblasts synthesize and release ET-1. Kinki University, Osaka,Japan
5. October 2005. Role of adventitia in vascular function. Tzu Chi University, Hualien, Taiwan.
6. December, 2003. NADPH oxidase in Angiotension II induced hypertension. Department of Anesthesia, Faculty of Health Sciences, McMaster Univr., Canada.
7. September, 2003. Superoxide anion and angiotensin II dependent hypertension. Dept of Biology, Brock University, Canada.
8. February, 2003. Role of NADPH Oxidase-Derived Superoxide in Angiotensin II-Induced Hypertension. Cardiology Research Round, St. Michael's Hospital, Univer. Toronto, Canada.
9. September, 2001. Role of NADPH oxidase in hypertension. Smooth Muscle Research Group, Faulty of Medicine, Univer. Calgary, Canada.
10. February 2000. Reduced pressure and hypertrophic responses to AII in gp91phox knockout mice: The role of NAD(P)H oxidase. Diabetes Workshop at the School of Medicine, Boston University, U.S.A.
11. January 2000. Reduced pressure responses to AII in gp91phox knockout mice: The role of NAD(P)H oxidase. Oxidative Stress Workshop at the School of Medicine, Boston University, U.S.A.
12. November 1999: Oxidative stress in AII-induced hypertension. Department of Physiology, School of Medicine, Univer. Minnesota, U.S.A.
13. August 1999: Role of adventitial superoxide anion in mediating spontaneous contraction in AII-induced hypertension. Veteran Medical Unit of Medical School, Univer. Minnesota, U.S.A
14. August 1997. Role of increased superoxide anion in mediating spontaneous contraction of aorta in AII-induced hypertension. Oxidative Stress Workshop at the School of Medicine, Boston University, U.S.A.
February 1997. Comparison of various methods for superoxide anion measurement in intact aorta. P Oxidative Stress Workshop at the School of Medicine, Boston University, U.S.A.
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